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Summary of When Less Is Not More: Large Language Models Normalize Less-frequent Terms with Lower Accuracy, by Daniel B. Hier and Thanh Son Do and Tayo Obafemi-ajayi


When Less Is Not More: Large Language Models Normalize Less-Frequent Terms with Lower Accuracy

by Daniel B. Hier, Thanh Son Do, Tayo Obafemi-Ajayi

First submitted to arxiv on: 11 Sep 2024

Categories

  • Main: Computation and Language (cs.CL)
  • Secondary: Artificial Intelligence (cs.AI)

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Summary difficulty Written by Summary
High Paper authors High Difficulty Summary
Read the original abstract here
Medium GrooveSquid.com (original content) Medium Difficulty Summary
A machine learning-based approach to normalize terms from free text to standardized concepts in the Human Phenotype Ontology (HPO) is crucial for precision medicine initiatives. Large language models like GPT-4o can perform this task but may retrieve incorrect HPO IDs, leading to inaccurate results. A study using a comprehensive dataset of 268,776 phenotype annotations found that GPT-4o achieved an accuracy of 13.1% in normalizing terms, with higher-frequency and shorter terms being normalized more accurately than lower-frequency and longer terms. Feature importance analysis identified low-term frequency as the most significant predictor of normalization errors. These findings suggest that training and evaluation datasets should balance low- and high-frequency terms to improve model performance, particularly for infrequent terms critical to precision medicine.
Low GrooveSquid.com (original content) Low Difficulty Summary
Term normalization is important for precision medicine because it helps match patients with similar diseases. A big language model called GPT-4o can do this job but sometimes gets it wrong. Researchers used a huge dataset of disease descriptions and found that GPT-4o got it right 13% of the time, but was better at matching common words than rare ones. This means we need to use more diverse training data to help the model make better predictions.

Keywords

» Artificial intelligence  » Gpt  » Language model  » Machine learning  » Precision