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Summary of Masked Autoencoders Are Scalable Learners Of Cellular Morphology, by Oren Kraus et al.


Masked Autoencoders are Scalable Learners of Cellular Morphology

by Oren Kraus, Kian Kenyon-Dean, Saber Saberian, Maryam Fallah, Peter McLean, Jess Leung, Vasudev Sharma, Ayla Khan, Jia Balakrishnan, Safiye Celik, Maciej Sypetkowski, Chi Vicky Cheng, Kristen Morse, Maureen Makes, Ben Mabey, Berton Earnshaw

First submitted to arxiv on: 27 Sep 2023

Categories

  • Main: Computer Vision and Pattern Recognition (cs.CV)
  • Secondary: Artificial Intelligence (cs.AI); Machine Learning (cs.LG)

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Summary difficulty Written by Summary
High Paper authors High Difficulty Summary
Read the original abstract here
Medium GrooveSquid.com (original content) Medium Difficulty Summary
This research paper explores the use of self-supervised deep learning approaches to infer biological relationships from cellular phenotypes in high-content microscopy screens. The study builds upon prior results showing that deep vision models can capture biological signal better than hand-crafted features, and aims to scale these methods for larger models and datasets. The authors find that both CNN- and ViT-based masked autoencoders outperform weakly supervised baselines, with a ViT-L/8 model trained on over 3.5-billion unique crops sampled from 93-million microscopy images achieving relative improvements of up to 28% compared to the best weakly supervised baseline.
Low GrooveSquid.com (original content) Low Difficulty Summary
This paper helps us better understand how cells work and what they do. It uses super powerful computers to look at tiny pictures of cells and figure out which ones are related. The researchers found that by using special computer programs, they can get even more accurate results than before. This is important because it will help scientists learn more about how cells work together and might even lead to new discoveries.

Keywords

* Artificial intelligence  * Cnn  * Deep learning  * Self supervised  * Supervised  * Vit