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Summary of Forecasting Disease Progression with Parallel Hyperplanes in Longitudinal Retinal Oct, by Arunava Chakravarty et al.


Forecasting Disease Progression with Parallel Hyperplanes in Longitudinal Retinal OCT

by Arunava Chakravarty, Taha Emre, Dmitrii Lachinov, Antoine Rivail, Hendrik Scholl, Lars Fritsche, Sobha Sivaprasad, Daniel Rueckert, Andrew Lotery, Ursula Schmidt-Erfurth, Hrvoje Bogunović

First submitted to arxiv on: 30 Sep 2024

Categories

  • Main: Computer Vision and Pattern Recognition (cs.CV)
  • Secondary: Artificial Intelligence (cs.AI); Machine Learning (cs.LG)

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GrooveSquid.com Paper Summaries

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Summary difficulty Written by Summary
High Paper authors High Difficulty Summary
Read the original abstract here
Medium GrooveSquid.com (original content) Medium Difficulty Summary
This research proposes a novel deep learning method for predicting the risk of late dry Age-related Macular Degeneration (dAMD) onset from retinal OCT scans. The approach jointly predicts a risk score inversely related to time-to-conversion and the probability of conversion within a specified time interval. It uses parallel hyperplanes parameterized by the bias term as a function of time, ensuring that risk scores increase over time and future conversion predictions are consistent with AMD stage prediction using actual scans from future visits. The method is designed to handle patient heterogeneity and subtle or unknown imaging biomarkers, and it can be fine-tuned on new datasets acquired with different scanners. The proposed approach achieves high mean AUROCs of 0.82 for Dataset-1 and 0.83 for Dataset-2 across prediction intervals of 6,12, and 24 months.
Low GrooveSquid.com (original content) Low Difficulty Summary
This paper develops a new way to predict the risk of age-related macular degeneration (AMD) from medical images. The researchers use special computer programs called deep learning methods that can analyze lots of data at once. They want to make sure their method works well on different kinds of scanners and with people who have different characteristics. To do this, they create a way to fine-tune their model using new data from other scanners. This helps the model be more accurate when it’s used on real patients. The results show that the method is good at predicting when someone will develop AMD, with accuracy scores of 0.82 and 0.83.

Keywords

» Artificial intelligence  » Deep learning  » Probability