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Summary of Classifying Cancer Stage with Open-source Clinical Large Language Models, by Chia-hsuan Chang et al.


Classifying Cancer Stage with Open-Source Clinical Large Language Models

by Chia-Hsuan Chang, Mary M. Lucas, Grace Lu-Yao, Christopher C. Yang

First submitted to arxiv on: 2 Apr 2024

Categories

  • Main: Computation and Language (cs.CL)
  • Secondary: Artificial Intelligence (cs.AI)

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GrooveSquid.com Paper Summaries

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Summary difficulty Written by Summary
High Paper authors High Difficulty Summary
Read the original abstract here
Medium GrooveSquid.com (original content) Medium Difficulty Summary
A novel approach to extract pathologic tumor-node-metastasis (pTNM) staging information from unstructured clinical reports in electronic health records is proposed. This method leverages open-source clinical large language models (LLMs), eliminating the need for labor-intensive labeled training datasets. The study compares LLMs with a BERT-based model fine-tuned using labeled data, demonstrating that while LLMs struggle with Tumor (T) classification, they can achieve comparable performance on Metastasis (M) classification and improved performance on Node (N) classification with suitable prompting strategies.
Low GrooveSquid.com (original content) Low Difficulty Summary
Doctors need to know the stage of a patient’s cancer to decide the best treatment. Right now, this information is often buried in unstructured reports from different healthcare providers. To help, researchers developed a way for computers to extract this important information without needing special training data. Instead, they used large language models that can learn from general medical texts. The results show that these models are good at identifying whether cancer has spread to lymph nodes or other parts of the body, but still need some improvement in understanding how far the cancer has grown.

Keywords

» Artificial intelligence  » Bert  » Classification  » Prompting