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Summary of Diffusion-based Generation Of Neural Activity From Disentangled Latent Codes, by Jonathan D. Mccart et al.


Diffusion-Based Generation of Neural Activity from Disentangled Latent Codes

by Jonathan D. McCart, Andrew R. Sedler, Christopher Versteeg, Domenick Mifsud, Mattia Rigotti-Thompson, Chethan Pandarinath

First submitted to arxiv on: 30 Jul 2024

Categories

  • Main: Machine Learning (cs.LG)
  • Secondary: Neurons and Cognition (q-bio.NC)

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Summary difficulty Written by Summary
High Paper authors High Difficulty Summary
Read the original abstract here
Medium GrooveSquid.com (original content) Medium Difficulty Summary
The proposed approach leverages conditional generative modeling and InfoDiffusion to enable unsupervised inference of disentangled behavioral variables from recorded neural activity. The model, Generating Neural Observations Conditioned on Codes with High Information (GNOCCHI), is applied to time series neural data and compared to a VAE-based sequential autoencoder. GNOCCHI learns higher-quality latent spaces that are more structured and disentangled, enabling accurate generation of novel samples through simple linear traversal.
Low GrooveSquid.com (original content) Low Difficulty Summary
Scientists have developed new ways to record brain activity from thousands of neurons at once. This has led to the development of new methods for analyzing this data. The proposed method uses a type of generative model to find patterns in the data that can be used to predict what would happen if certain conditions were different. This could help researchers understand how the brain works and make predictions about behavior. The method is tested on real and simulated data from reaching tasks.

Keywords

* Artificial intelligence  * Autoencoder  * Generative model  * Inference  * Time series  * Unsupervised