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Summary of Simple, Efficient and Scalable Structure-aware Adapter Boosts Protein Language Models, by Yang Tan et al.


Simple, Efficient and Scalable Structure-aware Adapter Boosts Protein Language Models

by Yang Tan, Mingchen Li, Bingxin Zhou, Bozitao Zhong, Lirong Zheng, Pan Tan, Ziyi Zhou, Huiqun Yu, Guisheng Fan, Liang Hong

First submitted to arxiv on: 23 Apr 2024

Categories

  • Main: Computation and Language (cs.CL)
  • Secondary: Machine Learning (cs.LG); Biomolecules (q-bio.BM)

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GrooveSquid.com Paper Summaries

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Summary difficulty Written by Summary
High Paper authors High Difficulty Summary
Read the original abstract here
Medium GrooveSquid.com (original content) Medium Difficulty Summary
This paper explores the application of fine-tuning pre-trained protein language models (PLMs) for enhancing downstream prediction tasks, which has shown to outperform traditional supervised learning approaches. The authors propose a novel adapter method called SES-Adapter, which combines PLM embeddings with structural sequence embeddings to create structure-aware representations. This approach is compatible with various PLM architectures and can be applied across different downstream tasks. Experimental results show that SES-Adapter improves task performance by up to 11% and accelerates training speed by up to 1034%, while also achieving faster convergence rates.
Low GrooveSquid.com (original content) Low Difficulty Summary
This paper helps scientists learn how to improve the way they use language models for protein prediction. The researchers develop a new method called SES-Adapter, which makes these models better at recognizing patterns in proteins. They test this method on different types of protein structures and show that it works well across many tasks. This means that scientists can now use language models to make more accurate predictions about protein behavior.

Keywords

» Artificial intelligence  » Fine tuning  » Supervised